Longitudinal Blood Transcriptome Analysis Reveals Dynamic Gene Expression Patterns in Patients With Allergic Rhinitis Following House Dust Mite Subcutaneous Immunotherapy
SCIT dynamically modulates blood gene expression profiles in AR patients, inducing immune tolerance and reducing inflammatory responses. These findings enhance understanding of the molecular mechanisms of SCIT and highlight potential biomarkers for predicting and monitoring treatment efficacy.
Authors
- Kanghua Wang (ORCID: https://orcid.org/0000-0001-9829-1640)
- Jincai Zhu (ORCID: https://orcid.org/0000-0001-7998-9373)
- JVG Rama Rao
- Yueqi Sun (ORCID: https://orcid.org/0000-0002-2382-0429)
- Chang Liu (ORCID: https://orcid.org/0000-0002-5717-3370)
- Shikun He
- Jinxiu Zhang (ORCID: https://orcid.org/0000-0003-1422-6126)
- Yunping Fan
Institutions
- Sun Yat-sen University (CN)
- The Seventh Affiliated Hospital of Sun Yat-sen University (CN)
Publication Details
- Journal
- Clinical & Experimental Allergy
- Published
- 2025-10-14
- DOI
- https://doi.org/10.1111/cea.70158
- Primary Topic
- Allergic Rhinitis and Sensitization
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Shenzhen Fundamental Research Program
- Sanming Project of Medicine in Shenzhen
- Basic and Applied Basic Research Foundation of Guangdong Province