Assessing effects of pneumococcal vaccination (PCV13) and rotavirus vaccination (RV) on colonization with extended-spectrum cephalosporin-resistant Enterobacterales (ESCrE) in Guatemalan children
Vaccination for pneumococcal disease was associated with a reduction in colonization with ESCrE bacteria. Antibiotic use did not contribute directly or indirectly to ESCrE colonization. These findings should be confirmed through studies designed to collect clinical outcomes data. Findings from this and other studies suggest that ESCrE colonization is mediated by a complex interplay of factors.
Authors
- J. Carlos Romero (ORCID: https://orcid.org/0000-0002-3474-4951)
- Natalie Fahsen (ORCID: https://orcid.org/0009-0001-3991-7524)
- Brooke M. Ramay (ORCID: https://orcid.org/0000-0001-8527-4067)
- Jonathan Yoder (ORCID: https://orcid.org/0000-0002-9049-9591)
- Laura M. Grajeda (ORCID: https://orcid.org/0000-0001-5386-4839)
- Guy H. Palmer (ORCID: https://orcid.org/0000-0001-5679-4709)
- Douglas R. Call (ORCID: https://orcid.org/0000-0001-6791-055X)
- Celia Cordón‐Rosales (ORCID: https://orcid.org/0000-0003-2381-4173)
- Carmen Castillo (ORCID: https://orcid.org/0000-0003-0495-1949)
- María Reneé López
- Lucas F Santos
Institutions
- Washington State University (US)
- Universidad del Valle de Guatemala (GT)
Publication Details
- Journal
- Vaccine
- Published
- 2025-10-13
- DOI
- https://doi.org/10.1016/j.vaccine.2025.127852
- Primary Topic
- Viral gastroenteritis research and epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00