Assessment of genetic and metabolite associations of branched chain amino acids with metabolic disease in the UK Biobank using Mendelian randomization
Overall, the results of our study highlight a relatively unexplored area of metabolite-disease associations and provide a blueprint for uncovering additional relationships using readily available biobank data.
Authors
- Courtney Astore (ORCID: https://orcid.org/0000-0002-3854-7250)
- Greg C. Gibson (ORCID: https://orcid.org/0000-0002-5352-5877)
- Jedrzej Konarkowski
Institutions
- Georgia Institute of Technology (US)
Publication Details
- Journal
- BMC Medical Genomics
- Published
- 2025-10-16
- DOI
- https://doi.org/10.1186/s12920-025-02232-2
- Primary Topic
- Genetic Associations and Epidemiology
- Type
- article
- Field-Weighted Citation Impact
- 0.00