Frequent <scp> <i>BRAF V600E</i> </scp> and <scp> <i>TERT</i> </scp> promoter‐mutated renal epithelial‐predominant Wilms tumours with metanephric features: a distinct subset within the Wilms tumour spectrum?
Our research supports the notion previously described that epithelial-predominant Wilms tumours, characterized by frequent TERT promoter and BRAF V600E mutations, represent a distinct subset within the Wilms tumour spectrum. These tumours display an expression profile closely resembling that of metanephric adenomas and are associated with a favourable prognosis.
Authors
- Qiu Rao (ORCID: https://orcid.org/0000-0002-2674-1937)
- Jiong Shi (ORCID: https://orcid.org/0000-0001-7548-7616)
- Yao Fu (ORCID: https://orcid.org/0000-0001-9864-1030)
- Jin Chen (ORCID: https://orcid.org/0000-0003-4410-6547)
- Qi Tong (ORCID: https://orcid.org/0000-0003-2498-4166)
- Jieyu Chen (ORCID: https://orcid.org/0000-0002-7886-367X)
- Ru Fang (ORCID: https://orcid.org/0000-0002-4041-211X)
- Qiuyuan Xia
- Yuemei Xu (ORCID: https://orcid.org/0000-0002-0223-7146)
- Xiaotong Wang
- Ya Wang (ORCID: https://orcid.org/0000-0001-5764-6740)
Institutions
- Anhui Medical University (CN)
- Nanjing General Hospital of Nanjing Military Command (CN)
- Nanjing Drum Tower Hospital (CN)
- First Affiliated Hospital of Anhui Medical University (CN)
- Second Affiliated Hospital of Nanjing Medical University (CN)
- Nanjing Medical University (CN)
- Nanjing University (CN)
Publication Details
- Journal
- Histopathology
- Published
- 2025-10-16
- DOI
- https://doi.org/10.1111/his.70022
- Primary Topic
- Renal and related cancers
- Type
- article
- Field-Weighted Citation Impact
- 0.00