Stereoselective synthesis of <i>C</i> -aryl glycosides <i>via</i> radical-enabled 1,4-Ni migration: glycosyl chlorides as coupling partners
Ni-catalyzed 1,4-migration enables stereoselective C -aryl glycoside synthesis from aryl halides and glycosyl chlorides. This directing-group-free method is mild, scalable, and proceeds via a radical mechanism with reversible Ni( ii ) migration.
Authors
- Zhi‐Jie Niu
- Xue‐Ya Gou (ORCID: https://orcid.org/0009-0008-7489-0014)
- Xi Chen (ORCID: https://orcid.org/0000-0001-7303-148X)
- Li Qiao (ORCID: https://orcid.org/0000-0002-0645-7496)
- Jinhui Yang (ORCID: https://orcid.org/0000-0003-0159-1669)
- Xiaoping Gong
- Hu-Yi Li
- Xue‐Yuan Liu (ORCID: https://orcid.org/0000-0002-8862-9924)
- Yong‐Min Liang (ORCID: https://orcid.org/0000-0001-8280-8211)
Institutions
- Ningxia University (CN)
- Lanzhou Jiaotong University (CN)
- Lanzhou University (CN)
Publication Details
- Journal
- Organic Chemistry Frontiers
- Published
- 2025-10-16
- DOI
- https://doi.org/10.1039/d5qo01241d
- Citations
- 1
- Primary Topic
- Carbohydrate Chemistry and Synthesis
- Type
- article
- Field-Weighted Citation Impact
- 0.94