Nonlinear associations between reported childhood trauma and cognitive impairment in schizophrenia spectrum disorders
We provide novel evidence for nonlinear associations between trauma and cognition, which may account for discrepancy among existing studies and suggest sensitivity of neural substrates of memory to particular levels of trauma. Our results also indicate that some of the cognitive deficits in schizophrenia may be attributed to the influence of early environmental factors.
Authors
- Arielle Ered (ORCID: https://orcid.org/0000-0002-8386-4423)
- Neil D. Woodward (ORCID: https://orcid.org/0000-0002-7472-5990)
- Stephan Heckers (ORCID: https://orcid.org/0000-0003-3601-9910)
- Julia M. Sheffield (ORCID: https://orcid.org/0000-0003-4173-9330)
- Jinyuan Liu (ORCID: https://orcid.org/0000-0001-6689-8245)
- Giancarlo Enzo Denaroso
Institutions
- University of Pennsylvania (US)
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Schizophrenia Research
- Published
- 2025-10-16
- DOI
- https://doi.org/10.1016/j.schres.2025.09.028
- Primary Topic
- Child and Adolescent Psychosocial and Emotional Development
- Type
- article
- Field-Weighted Citation Impact
- 0.00