Recurrence of Atypical Meningioma: A Case Report

Atypical meningiomas are classified by the World Health Organization (WHO) as grade II central nervous system tumors, representing an intermediate biological profile between benign (grade I) and anaplastic (grade III) variants. They are defined by elevated mitotic activity, invasive growth patterns, and distinct histopathological features such as hypercellularity, small cell morphology, prominent nucleoli, and areas of necrosis. Clinically, these tumors often manifest with neurological symptoms - headaches, seizures, focal neurological deficits, personality alterations, or visual impairment - depending on their anatomical location. On imaging, atypical meningiomas typically show either homogeneous or heterogeneous contrast enhancement, surrounding edema, and exert mass effect on adjacent brain structures. MRI and MR spectroscopy help in assessing these cases. Surgery tends to be the main treatment, but recurrence is more common than what's typically seen in grade I meningiomas. Adjuvant radiotherapy is frequently recommended, particularly in cases of subtotal resection or when high-risk features are present. Given their aggressive behavior and propensity for recurrence or malignant progression, comprehensive multidisciplinary care and close surveillance are critical to achieving optimal clinical outcomes. In this case, we present a 57-year-old gentleman diagnosed with peritorcular meningioma.

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Publication Details

Journal
Cureus
Published
2025-10-15
DOI
https://doi.org/10.7759/cureus.94686
Primary Topic
Meningioma and schwannoma management
Type
article
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article

Recurrence of Atypical Meningioma: A Case Report

Satish Patel, Silpa Mary Johnson, Anand Paul
Cureus
Meningioma and schwannoma management
article

Recurrence of Atypical Meningioma: A Case Report

Satish Patel, Silpa Mary Johnson, Anand Paul
article en

Abstract

Atypical meningiomas are classified by the World Health Organization (WHO) as grade II central nervous system tumors, representing an intermediate biological profile between benign (grade I) and anaplastic (grade III) variants. They are defined by elevated mitotic activity, invasive growth patterns, and distinct histopathological features such as hypercellularity, small cell morphology, prominent nucleoli, and areas of necrosis. Clinically, these tumors often manifest with neurological symptoms - headaches, seizures, focal neurological deficits, personality alterations, or visual impairment - depending on their anatomical location. On imaging, atypical meningiomas typically show either homogeneous or heterogeneous contrast enhancement, surrounding edema, and exert mass effect on adjacent brain structures. MRI and MR spectroscopy help in assessing these cases. Surgery tends to be the main treatment, but recurrence is more common than what's typically seen in grade I meningiomas. Adjuvant radiotherapy is frequently recommended, particularly in cases of subtotal resection or when high-risk features are present. Given their aggressive behavior and propensity for recurrence or malignant progression, comprehensive multidisciplinary care and close surveillance are critical to achieving optimal clinical outcomes. In this case, we present a 57-year-old gentleman diagnosed with peritorcular meningioma.

CureusVol. 17(10)
Government Medical College and Hospital (IN), Royal Blackburn Teaching Hospital (GB), Government Medical College (IN), Blackburn College (US)
Openalex Percentile: Top 61%
Meningioma and schwannoma management
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Recurrence of Atypical Meningioma: A Case Report — Satish Patel, Silpa Mary Johnson, et al. · Cureus (2025) | TGRS Research Map | TGRS