Current status of Helicobacter pylori infection and prevalence of resistance-associated gene mutations in Bortala Mongolian Autonomous Prefecture, Xinjiang: a single-center study

The Bortala Prefecture exhibits alarming genotypic resistance patterns to first-line antibiotics, despite a moderate <i>H. pylori</i> infection prevalence. These findings underscore the critical need for region-specific antimicrobial stewardship and evidence-based treatment protocols guided by local resistance profiles. Future research should prioritize stratified sampling methodologies to delineate ethnicity-specific risk profiles and validate potential risk factors in larger cohorts.