The association between peripheral blood inflammatory markers and anti-VEGF treatment response in patients with type 2 diabetic macular edema
The efficacy of anti-VEGF in DME is correlated with serum inflammatory markers. Additionally, NLR, PLR, MLR, and SII may serve as potential markers for DME treatment decisions. The finding that NLR remained significant in the multivariate analysis highlights its potential value as a simple, accessible prognostic biomarker for stratifying patients who may respond suboptimally to anti-VEGF treatment.
Authors
- Tingting Xu
- Zhizhe Li
- Min Wang (ORCID: https://orcid.org/0000-0002-4067-9068)
- Wenting Gu
Institutions
- Nantong University (CN)
- Affiliated Hospital of Nantong University (CN)
- Suzhou Municipal Hospital (CN)
Publication Details
- Journal
- Frontiers in Medicine
- Published
- 2025-10-16
- DOI
- https://doi.org/10.3389/fmed.2025.1653753
- Citations
- 2
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 3.41