B cell subpopulations and their role in the pathogenesis of primary Sjögren’s syndrome: insights from single-cell RNA sequencing
B cells contribute to the pathogenesis of pSS through the Type I IFN signaling pathway mediated by genes such as ISG15, alterations in BCR clonality, IGHV-J gene rearrangements, and abnormal gene usage.
Authors
- Bin Liu (ORCID: https://orcid.org/0000-0001-7489-9125)
- Hong Zhu (ORCID: https://orcid.org/0000-0002-3187-7361)
- Yu Song (ORCID: https://orcid.org/0000-0002-2123-934X)
- Jinhai Tian (ORCID: https://orcid.org/0000-0002-4823-9323)
- Jing Zhang (ORCID: https://orcid.org/0000-0003-3733-8104)
- Xiaoyu Zhang (ORCID: https://orcid.org/0000-0001-9428-0813)
- Yan Zhou (ORCID: https://orcid.org/0000-0003-3379-2369)
- Jia Wang (ORCID: https://orcid.org/0000-0002-2538-6224)
- Fang Li (ORCID: https://orcid.org/0000-0003-0371-1687)
- Yanni Han (ORCID: https://orcid.org/0000-0001-6820-4219)
- Xinran Xin
Institutions
- Qingdao University (CN)
- Affiliated Hospital of Qingdao University (CN)
- Ningxia Medical University (CN)
- Wuxi Vocational Institute of Commerce (CN)
- Ningxia Medical University General Hospital (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-10-16
- DOI
- https://doi.org/10.3389/fimmu.2025.1665086
- Citations
- 3
- Primary Topic
- Salivary Gland Disorders and Functions
- Type
- article
- Field-Weighted Citation Impact
- 3.49