Successful thrombolysis of portal vein thrombosis induced by post-liver transplant splenectomy: a case report

This case underscores the importance of early detection, tailored anticoagulation strategies, and a multidisciplinary approach in managing PVT following splenectomy in LT recipients. Peripheral urokinase infusion may serve as a viable treatment option for patients with contraindications or reluctance toward invasive procedures. Further studies are needed to optimize anticoagulation protocols and long-term management strategies in this patient population.

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Publication Details

Journal
Frontiers in Transplantation
Published
2025-10-16
DOI
https://doi.org/10.3389/frtra.2025.1689539
Primary Topic
Liver Disease and Transplantation
Type
article
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article

Successful thrombolysis of portal vein thrombosis induced by post-liver transplant splenectomy: a case report

Pusen Wang, Yiming Huang, Dong Zhao, Lin Zhong et al.
Frontiers in Transplantation
Liver Disease and Transplantation
article

Successful thrombolysis of portal vein thrombosis induced by post-liver transplant splenectomy: a case report

Pusen Wang, Yiming Huang, Dong Zhao, Lin Zhong, Xu Yan
article en

Abstract

This case underscores the importance of early detection, tailored anticoagulation strategies, and a multidisciplinary approach in managing PVT following splenectomy in LT recipients. Peripheral urokinase infusion may serve as a viable treatment option for patients with contraindications or reluctance toward invasive procedures. Further studies are needed to optimize anticoagulation protocols and long-term management strategies in this patient population.

Frontiers in TransplantationVol. 4
Kyoto University (JP), Southern University of Science and Technology (CN), Shenzhen Third People’s Hospital (CN)
Openalex Percentile: Top 61%
Liver Disease and Transplantation
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Successful thrombolysis of portal vein thrombosis induced by post-liver transplant splenectomy: a case report — Pusen Wang, Yiming Huang, et al. · Frontiers in Transplantation (2025) | TGRS Research Map | TGRS