A proteomic map of thromboinflammatory signatures in antiphospholipid syndrome: results from antiphospholipid syndrome alliance for clinical trials and international networking (APS ACTION) registry
Our findings provide novel insights into the pathogenesis of APS and identify potential novel targets for diagnostic and therapeutic intervention in APS across its entire spectrum.
Authors
- Sean X. Gu (ORCID: https://orcid.org/0000-0001-5505-3474)
- George Goshua (ORCID: https://orcid.org/0000-0002-1624-4427)
- Vittorio Pengo (ORCID: https://orcid.org/0000-0003-2064-6071)
- Irene Cecchi (ORCID: https://orcid.org/0000-0002-1858-5452)
- Nina Kello (ORCID: https://orcid.org/0000-0001-5497-7472)
- Doruk Erkan (ORCID: https://orcid.org/0000-0001-7216-677X)
- Pier Luigi Meroni (ORCID: https://orcid.org/0000-0002-3394-1451)
- Ricard Cervera (ORCID: https://orcid.org/0000-0001-6085-492X)
- Alfred Ian Lee (ORCID: https://orcid.org/0000-0002-5968-3948)
- H. Michael Belmont (ORCID: https://orcid.org/0000-0003-3389-2976)
- Rohan Willis (ORCID: https://orcid.org/0000-0002-1374-7678)
- Laura Andréoli (ORCID: https://orcid.org/0000-0002-9107-3218)
- Alexander B. Pine (ORCID: https://orcid.org/0000-0002-9463-3022)
- C. López-Pedrera (ORCID: https://orcid.org/0000-0003-2067-4603)
- D. Ware Branch (ORCID: https://orcid.org/0000-0002-1718-5094)
- Hannah Cohen (ORCID: https://orcid.org/0000-0003-2032-390X)
- Maria Gerosa (ORCID: https://orcid.org/0000-0001-5241-5847)
- Ayesha Butt (ORCID: https://orcid.org/0000-0003-1172-2159)
- Anish V. Sharda (ORCID: https://orcid.org/0000-0003-3856-4277)
- John Hwa (ORCID: https://orcid.org/0000-0001-7366-2628)
- Jason S. Knight (ORCID: https://orcid.org/0000-0003-0995-9771)
- Michelle Petri
- Maria Laura Bertolccini
Institutions
- Intermountain Healthcare (US)
- Hospital for Special Surgery (US)
- Northwell Health (US)
- St Thomas' Hospital (GB)
- University of Padua (IT)
- Johns Hopkins University (US)
- University of Milan (IT)
- Cornell University (US)
- University of Michigan (US)
- Johns Hopkins Medicine (US)
- Yale University (US)
- NYU Langone Health (US)
- Instituto Maimónides de Investigación Biomédica de Córdoba (ES)
- Michigan Medicine (US)
- Department of Medical Sciences (BY)
- Mylan (Switzerland) (CH)
- The London College (GB)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
- University College London (GB)
- University of Turin (IT)
- The University of Texas Medical Branch at Galveston (US)
- University of Brescia (IT)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-10-16
- DOI
- https://doi.org/10.3389/fimmu.2025.1676578
- Citations
- 5
- Primary Topic
- Systemic Lupus Erythematosus Research
- Type
- article
- Field-Weighted Citation Impact
- 8.34
Funders
- Yale University
- Yale Cancer Center