Macrophage activation syndrome-like in multiple myeloma patients treated with the academic CAR-T against BCMA ARI0002h
MAS-<i>like</i> is associated with poorer responses, reduced PFS and OS, especially in patients meeting all UCSF criteria. High tumour burden, including elevated monoclonal component, high ISS and extramedullary disease, seems to contribute to MAS-<i>like</i> development.
Authors
- Juan Luis Reguera (ORCID: https://orcid.org/0009-0009-6408-1747)
- Sara Varea (ORCID: https://orcid.org/0000-0002-0002-6492)
- Álvaro Urbano-Ispizúa (ORCID: https://orcid.org/0000-0002-7529-9399)
- Julio Delgado (ORCID: https://orcid.org/0000-0002-5157-4376)
- Cristina Arnaldos‐Perez (ORCID: https://orcid.org/0000-0002-7188-5411)
- Luis Gerardo Rodríguez‐Lobato (ORCID: https://orcid.org/0000-0001-5694-0921)
- María‐Victoria Mateos (ORCID: https://orcid.org/0000-0003-2390-1218)
- Joaquín Martínez‐López (ORCID: https://orcid.org/0000-0001-7908-0063)
- Natalia Tovar (ORCID: https://orcid.org/0000-0001-5525-476X)
- Elena Guillén (ORCID: https://orcid.org/0000-0002-5687-5549)
- Carlos Fernández de Larrea (ORCID: https://orcid.org/0000-0003-4930-9255)
- Verónica González‐Calle (ORCID: https://orcid.org/0000-0002-5493-6707)
- Aina Oliver‐Caldés (ORCID: https://orcid.org/0000-0002-7921-5420)
- Lucía López‐Corral (ORCID: https://orcid.org/0000-0003-1908-5596)
- Nieves López‐Muñoz (ORCID: https://orcid.org/0000-0003-0090-6673)
- Valentín Cabañas (ORCID: https://orcid.org/0000-0002-6248-2549)
- Europa Azucena González‐Navarro (ORCID: https://orcid.org/0000-0003-3310-5557)
- Juan Carlos Ponce
- José M. Moraleda (ORCID: https://orcid.org/0000-0001-9080-1466)
- Núria Martínez‐Cibrián (ORCID: https://orcid.org/0000-0002-8688-1202)
- Paula Rodríguez‐Otero (ORCID: https://orcid.org/0000-0001-5236-7785)
- Daniel Munárriz
- Ana África Martín
Institutions
- Research Institute Hospital 12 de Octubre (ES)
- Navarre Institute of Health Research (ES)
- Instituto de Biomedicina de Sevilla (ES)
- Centro de Investigación del Cáncer (ES)
- Instituto Murciano de Investigación Biosanitaria (ES)
- Centro de Investigación Biomédica en Red de Cáncer (ES)
- Consorci Institut D'Investigacions Biomediques August Pi I Sunyer (ES)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-10-16
- DOI
- https://doi.org/10.3389/fimmu.2025.1654096
- Primary Topic
- Autoimmune and Inflammatory Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- “la Caixa” Foundation
- European Commission
- Generalitat de Catalunya
- Universidad de Navarra
- CRIS Cancer Foundation
- Agència de Gestió d'Ajuts Universitaris i de Recerca
- Instituto de Salud Carlos III
- European Regional Development Fund