Proteomic profiling of cerebrospinal fluid uncovers distinctive pathophysiological changes and potential biomarkers in pediatric tubercular meningitis
This research will provide a highly valuable proteomics resource for a better understanding of TBM pathogenesis, yielding insights into important differential diagnostic biomarkers and potential therapeutic targets in pediatric TBM.
Authors
- Liang Zhu (ORCID: https://orcid.org/0000-0002-6529-5706)
- Peng Guo (ORCID: https://orcid.org/0000-0002-5435-5523)
- Yuncui Yu
- Zhenzhen Dou
- Bing Hu (ORCID: https://orcid.org/0000-0001-5085-3114)
- Binglin Jian
- Lingyun Guo (ORCID: https://orcid.org/0000-0001-9021-4341)
- Huili Hu (ORCID: https://orcid.org/0000-0002-1239-7127)
- Linlin Liu (ORCID: https://orcid.org/0000-0001-5093-7940)
- Gang Liu (ORCID: https://orcid.org/0000-0003-2492-4833)
- Jing Wei (ORCID: https://orcid.org/0000-0001-7457-0688)
Institutions
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Beijing Children’s Hospital (CN)
Publication Details
- Journal
- Frontiers in Cellular and Infection Microbiology
- Published
- 2025-10-16
- DOI
- https://doi.org/10.3389/fcimb.2025.1662783
- Primary Topic
- Infectious Diseases and Tuberculosis
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Natural Science Foundation of China
- Beijing Municipal Administration of Hospitals