Electrical impedance tomography to guide mechanical ventilation for asymmetrical lung injury: a case report

During last years, new methods of advanced ventilatory monitoring have been introduced to implement lung-protective ventilation. We present a unique case of a 66-year-old female admitted to the ICU with severe unilateral lung injury due to COVID-19 pneumococcal superinfection. By combining electrical impedance tomography (EIT) and esophageal pressure measurements, individualized positive end-expiratory pressure (PEEP) titration was performed. Initially, high PEEP levels (18 cmH<sub>2</sub>O) were optimal. Over the course of a week, reflecting dynamic lung recovery, PEEP levels could be reduced to 8 cmH<sub>2</sub>O followed by extubation. This case emphasizes the importance of personalized PEEP titration in managing asymmetric lung injury, highlighting how EIT-based monitoring can optimize alveolar recruitment while minimizing overdistension.

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Publication Details

Journal
Frontiers in Medicine
Published
2025-10-16
DOI
https://doi.org/10.3389/fmed.2025.1675679
Primary Topic
Respiratory Support and Mechanisms
Type
article
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article

Electrical impedance tomography to guide mechanical ventilation for asymmetrical lung injury: a case report

Corstiaan A. den Uil, Dolf Weller, Albina Musaj, Louis Tronchet
Frontiers in Medicine
Respiratory Support and Mechanisms
article

Electrical impedance tomography to guide mechanical ventilation for asymmetrical lung injury: a case report

Corstiaan A. den Uil, Dolf Weller, Albina Musaj, Louis Tronchet
article en

Abstract

During last years, new methods of advanced ventilatory monitoring have been introduced to implement lung-protective ventilation. We present a unique case of a 66-year-old female admitted to the ICU with severe unilateral lung injury due to COVID-19 pneumococcal superinfection. By combining electrical impedance tomography (EIT) and esophageal pressure measurements, individualized positive end-expiratory pressure (PEEP) titration was performed. Initially, high PEEP levels (18 cmH<sub>2</sub>O) were optimal. Over the course of a week, reflecting dynamic lung recovery, PEEP levels could be reduced to 8 cmH<sub>2</sub>O followed by extubation. This case emphasizes the importance of personalized PEEP titration in managing asymmetric lung injury, highlighting how EIT-based monitoring can optimize alveolar recruitment while minimizing overdistension.

Frontiers in MedicineVol. 12
Maasstad Ziekenhuis (NL)
Openalex Percentile: Top 58%
Respiratory Support and Mechanisms
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Electrical impedance tomography to guide mechanical ventilation for asymmetrical lung injury: a case report — Corstiaan A. den Uil, Dolf Weller, et al. · Frontiers in Medicine (2025) | TGRS Research Map | TGRS