Mediating role of brain aging in the effect of white matter hyperintensities on post-stroke aphasia severity
Our findings highlight the influence of neuroanatomical aging and WMH burden on post-stroke language deficits, supporting the consideration of both brain-PAD and WMH severity when assessing aphasia severity to inform clinical assessment and treatment planning.
Authors
- Guihua Xu (ORCID: https://orcid.org/0000-0001-5245-3253)
- Wenwen Xu (ORCID: https://orcid.org/0000-0002-4813-0715)
- Rui Zhu (ORCID: https://orcid.org/0000-0001-9387-9672)
- Dawei Wang (ORCID: https://orcid.org/0000-0002-4488-2135)
- Junyu Qu (ORCID: https://orcid.org/0009-0005-2970-5068)
- Jiaxiang Xin
- Yongsheng Wu (ORCID: https://orcid.org/0009-0005-7712-6917)
Institutions
- University of Jinan (CN)
- High Magnetic Field Laboratory (CN)
- Siemens Healthcare (United States) (US)
- Qilu Hospital of Shandong University (CN)
Publication Details
- Journal
- Frontiers in Aging Neuroscience
- Published
- 2025-10-16
- DOI
- https://doi.org/10.3389/fnagi.2025.1629870
- Primary Topic
- Advanced MRI Techniques and Applications
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Natural Science Foundation of Shandong Province