Patients with anti-SAE+ dermatomyositis display refractory and difficult-to-treat skin manifestations: case series from two Italian cohorts and review of literature
All patients with anti-SAE antibody positivity were classified as having dermatomyositis, with severe and refractory skin manifestations in most cases. One case of malignancy was described; therefore, cancer screening should be warranted in all anti-SAE patients.
Authors
- Chiara Franco (ORCID: https://orcid.org/0000-0001-9027-511X)
- Mariele Gatto (ORCID: https://orcid.org/0000-0003-4012-1248)
- Stefano Piaserico (ORCID: https://orcid.org/0000-0002-1091-4733)
- Elena Treppo (ORCID: https://orcid.org/0000-0002-4731-9882)
- Roberto Depascale
- Federico Pettorossi
- Beatrice Moccaldi (ORCID: https://orcid.org/0000-0002-3162-783X)
- Luca Quartuccio (ORCID: https://orcid.org/0000-0002-0134-6439)
- Andrea Doria (ORCID: https://orcid.org/0000-0003-0548-4983)
- Christian Ciolfi (ORCID: https://orcid.org/0000-0002-9098-4124)
- Luca Iaccarino (ORCID: https://orcid.org/0000-0001-7870-425X)
- Anna Ghirardello
- Marco Bracalenti (ORCID: https://orcid.org/0000-0002-8768-3793)
- Margherita Zen (ORCID: https://orcid.org/0000-0003-0835-1406)
- Elisabetta Zanatta (ORCID: https://orcid.org/0000-0002-4845-5413)
Institutions
- University of Udine (IT)
- University of Padua (IT)
- A. O. Ordine Mauriziano di Torino (IT)
- University of Turin (IT)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-10-16
- DOI
- https://doi.org/10.3389/fimmu.2025.1597282
- Primary Topic
- Inflammatory Myopathies and Dermatomyositis
- Type
- article
- Field-Weighted Citation Impact
- 0.00