Mitochondrial quality control in neurodegenerative diseases: from molecular mechanisms to natural product therapies
This review summarizes the functional characteristics and biological events of mitochondrial quality control systems in neurodegenerative diseases pathogenesis, and comprehensively analyzes the pharmacological mechanisms by which natural products regulate mitochondrial quality control to improve neurodegenerative diseases, aiming to provide a scientific basis for further research and new clinical drug development.
Authors
- Qingzhi Liu (ORCID: https://orcid.org/0000-0003-2621-9222)
- Qi Liu (ORCID: https://orcid.org/0000-0002-3740-1321)
- Boxun Chen
- Xuedong Zhou (ORCID: https://orcid.org/0000-0002-9319-7302)
- Hongying Mao (ORCID: https://orcid.org/0000-0002-7950-2534)
- Yannan Wang (ORCID: https://orcid.org/0000-0001-7248-4954)
- Qing Wang (ORCID: https://orcid.org/0000-0002-0004-6418)
- Jiamin Li (ORCID: https://orcid.org/0000-0002-4527-3147)
- Weiyue Chen (ORCID: https://orcid.org/0000-0002-1313-0168)
Institutions
- Shandong University of Traditional Chinese Medicine (CN)
- Beijing University of Chinese Medicine (CN)
- Affiliated Hospital of Shandong University of Traditional Chinese Medicine (CN)
Publication Details
- Journal
- Frontiers in Physiology
- Published
- 2025-10-16
- DOI
- https://doi.org/10.3389/fphys.2025.1695681
- Citations
- 1
- Primary Topic
- Mitochondrial Function and Pathology
- Type
- article
- Field-Weighted Citation Impact
- 0.81