RARRES1 attenuates H2O2-induced RPE cell injury and inhibits choroidal neovascularization
RARRES1 protects retinal pigment epithelial cells from oxidative stress, inhibits choroidal neovascularization, and modulates inflammatory and angiogenic pathways. These findings identify RARRES1 as a potential biomarker and therapeutic target for nAMD.
Authors
- Renhao Xu (ORCID: https://orcid.org/0009-0000-8386-2869)
- Tao Deng (ORCID: https://orcid.org/0000-0002-8303-0891)
- Caixia Wang (ORCID: https://orcid.org/0009-0006-5730-6002)
- Xuejing Li (ORCID: https://orcid.org/0000-0001-7145-7225)
- Yimeng Li (ORCID: https://orcid.org/0009-0005-7357-8473)
- Qingli Shang (ORCID: https://orcid.org/0000-0002-7276-286X)
Institutions
- Hebei Medical University (CN)
- Second Hospital of Hebei Medical University (CN)
Publication Details
- Journal
- Frontiers in Physiology
- Published
- 2025-10-16
- DOI
- https://doi.org/10.3389/fphys.2025.1641653
- Primary Topic
- Retinal Diseases and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00