Case Report: Diagnosis and treatment of giant thoracodorsal liposarcoma
Early detection and timely intervention of liposarcoma are critical, particularly for large liposarcomas in the thoracodorsal region because of the surrounding vital structures, such as the brachial plexus, axillary vein, and axillary artery. We found that the liposarcoma was infiltrated by M2 macrophages, with the central region exhibiting high rates of M0 macrophages and Treg cells. This immunosuppressive tumor microenvironment may provide a potential target for the development of immunotherapeutic strategies.
Authors
- Ningning Ren (ORCID: https://orcid.org/0000-0003-1182-1157)
- Y Li (ORCID: https://orcid.org/0000-0001-6963-0957)
- Xia Li (ORCID: https://orcid.org/0000-0002-4348-3175)
- Zhi‐Hao Wang (ORCID: https://orcid.org/0000-0001-9722-0429)
- Bowen Zhao (ORCID: https://orcid.org/0009-0001-4664-0228)
- Peng Zhao (ORCID: https://orcid.org/0000-0001-5208-5809)
- Kailin Liu (ORCID: https://orcid.org/0000-0003-1059-0334)
- Chong Geng
Institutions
- Second Affiliated Hospital of Zhengzhou University (CN)
- Shandong Provincial Hospital (CN)
- Shandong First Medical University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-10-16
- DOI
- https://doi.org/10.3389/fonc.2025.1570796
- Primary Topic
- Sarcoma Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00