Molecular Markers of Antimalarial Drug Resistance in <i>Plasmodium falciparum</i> From Kumasi, Ghana, 2023
While the efficacy of artemisinin-based combination treatment in Ghana is still high, isolated critical pfk13 polymorphisms were identified as well as a considerable prevalence of a potentially relevant pfcoronin marker, against a background of pfmdr1 signals for impaired lumefantrine sensitivity. Continuous molecular monitoring is necessary to detect threats to artemisinin-based combination treatment efficacy at an early stage.
Authors
- Frank P. Mockenhaupt (ORCID: https://orcid.org/0000-0002-8117-5421)
- Michael Ramharter (ORCID: https://orcid.org/0000-0002-9259-1885)
- Welmoed van Loon (ORCID: https://orcid.org/0000-0003-3331-3997)
- Richard Odame Phillips (ORCID: https://orcid.org/0000-0001-8992-0222)
- Clement Igiraneza
- Jules Ndoli (ORCID: https://orcid.org/0000-0001-6649-3547)
- Eric Darko (ORCID: https://orcid.org/0000-0002-7074-115X)
- Melina Heinemann (ORCID: https://orcid.org/0000-0001-7762-4696)
- Nana Kwame Ayisi‐Boateng (ORCID: https://orcid.org/0000-0002-0961-4434)
- E. Oppong
- Albert Dennis Kegya
Institutions
- Universität Hamburg (DE)
- University of Zurich (CH)
- Kwame Nkrumah University of Science and Technology (GH)
- University of Rwanda (RW)
- University Hospital of Zurich (CH)
- University Medical Center Hamburg-Eppendorf (DE)
- German Center for Infection Research (DE)
- Kumasi Centre for Collaborative Research in Tropical Medicine (GH)
- Berlin Institute of Health at Charité - Universitätsmedizin Berlin (DE)
- University Teaching Hospital of Butare (RW)
- Charité - Universitätsmedizin Berlin (DE)
- Bernhard Nocht Institute for Tropical Medicine (DE)
Publication Details
- Journal
- Tropical Medicine & International Health
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1111/tmi.70048
- Citations
- 1
- Primary Topic
- Malaria Research and Control
- Type
- article
- Field-Weighted Citation Impact
- 1.88
Funders
- Else Kröner-Fresenius-Stiftung
- Bundesministerium für Wirtschaftliche Zusammenarbeit und Entwicklung
- Kwame Nkrumah University of Science and Technology