Long-term anorectal function in rectal cancer patients managed by a watch-and-wait strategy after total neoadjuvant treatment: a cross-sectional study
Most rectal cancer patients under a W&W strategy after TNT sustain acceptable anorectal function, though fecal urgency remains a common issue. Smoking history emerged as a significant risk factor for anorectal dysfunction. Larger prospective studies focusing on bowel function are needed.
Authors
- Lin Xu (ORCID: https://orcid.org/0000-0001-7750-8011)
- Xian Wu (ORCID: https://orcid.org/0000-0002-6805-3737)
- Yan Xuan
- Hui Zhang (ORCID: https://orcid.org/0000-0002-5867-1478)
- Zhiyuan Zhang (ORCID: https://orcid.org/0000-0001-9067-0670)
- Jingwen Wang
- Fan Xia (ORCID: https://orcid.org/0000-0001-8185-8663)
- Xin Jin (ORCID: https://orcid.org/0000-0001-7858-8375)
- Yun Deng
- Zhen Zhang (ORCID: https://orcid.org/0009-0008-5840-3351)
Institutions
- Shanghai Medical College of Fudan University (CN)
- Fudan University (CN)
- Shanghai Stomatological Hospital (CN)
- Fudan University Shanghai Cancer Center (CN)
- Shanghai Institute of Hematology (CN)
Publication Details
- Journal
- Radiation Oncology
- Published
- 2025-10-16
- DOI
- https://doi.org/10.1186/s13014-025-02732-6
- Citations
- 2
- Primary Topic
- Colorectal Cancer Surgical Treatments
- Type
- article
- Field-Weighted Citation Impact
- 2.09
Funders
- Shanghai Anti-Cancer Association
- National Natural Science Foundation of China
- Fudan University