Fixed Dystonia of a Limb: Amputation Could Be a Favourable Outcome

Fixed dystonia of limb is a rare and complex disorder characterized by abnormal, fixed posturing of a limb, often accompanied by chronic pain. Its etiology remains controversial, with debates surrounding psychogenic versus organic origins. We present the case of a 22-year-old female with a longstanding history of left foot deformity and progressively worsening neuropathic pain, which persisted despite multiple pharmacological treatments, physiotherapy, and psychological interventions. The patient developed severe psychological distress, including suicidal ideation and a self-amputation attempt. After thorough multidisciplinary evaluation, an above-knee amputation was performed. Postoperatively, she experienced complete resolution of preoperative pain, minimal phantom pain managed conservatively, and regained full independence with a prosthesis. Her functional capacity and mental health improved significantly. This case highlights the extreme challenges of managing fixed dystonia and suggests that amputation, although controversial, may be beneficial in highly selected patients with intractable symptoms and significant psychosocial impact.

Authors

Institutions

Publication Details

Journal
Cureus
Published
2025-10-15
DOI
https://doi.org/10.7759/cureus.94671
Primary Topic
Botulinum Toxin and Related Neurological Disorders
Type
article
Field-Weighted Citation Impact
0.00
Controls
|||
ALL TIME
JAN
FEB
MAR
APR
MAY
JUN
JUL
AUG
SEP
OCT
article

Fixed Dystonia of a Limb: Amputation Could Be a Favourable Outcome

Ruhina Rana, Shivani Virpura, Yogendrasinh Jagatsinh
Cureus
Botulinum Toxin and Related Neurological Disorders
article

Fixed Dystonia of a Limb: Amputation Could Be a Favourable Outcome

Ruhina Rana, Shivani Virpura, Yogendrasinh Jagatsinh
article en

Abstract

Fixed dystonia of limb is a rare and complex disorder characterized by abnormal, fixed posturing of a limb, often accompanied by chronic pain. Its etiology remains controversial, with debates surrounding psychogenic versus organic origins. We present the case of a 22-year-old female with a longstanding history of left foot deformity and progressively worsening neuropathic pain, which persisted despite multiple pharmacological treatments, physiotherapy, and psychological interventions. The patient developed severe psychological distress, including suicidal ideation and a self-amputation attempt. After thorough multidisciplinary evaluation, an above-knee amputation was performed. Postoperatively, she experienced complete resolution of preoperative pain, minimal phantom pain managed conservatively, and regained full independence with a prosthesis. Her functional capacity and mental health improved significantly. This case highlights the extreme challenges of managing fixed dystonia and suggests that amputation, although controversial, may be beneficial in highly selected patients with intractable symptoms and significant psychosocial impact.

CureusVol. 17(10)
Cumberland Infirmary (GB)
Openalex Percentile: Top 58%
Botulinum Toxin and Related Neurological Disorders
AI Navigator

Ask Laika to Summarize, Analyze, and Connect papers live on the map.

Summarize Papers & Methodologies

Extract key findings, datasets, and comparative methods across publications.

Benchmark Rankings & Visual Analytics

Rank top research institutions, authors, funders, topics, and journals by Field-Weighted Citation Impact (FWCI) and paper volume with instant charts.

Connect Distant Disciplines

Bridge topological clusters on the map to find hidden collaborative intersections.