Adult Medulloblastoma Presenting With Audiovestibular Symptoms and an Alternating Unterberger Test

A man in his 30s presented with a four-week history of vertigo, unilateral tinnitus, and nausea on a background of a three-year history of asymmetric audiovestibular symptoms attributed to peripheral vestibular pathology. The neurological examination was normal. A brain magnetic resonance imaging (MRI) demonstrated a fourth ventricular enhancing tumour, which was resected. The final histology was classical medulloblastoma CNS WHO Grade 4. He received craniospinal irradiation and adjuvant chemotherapy. Two years after treatment, he relapsed with spinal drop metastases and received palliative treatment. This case highlights that adults with medulloblastoma may present atypically with a longer history of unusual audiovestibular symptoms rather than signs of raised intracranial pressure or brainstem/cerebellar dysfunction.

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Publication Details

Journal
Cureus
Published
2025-10-15
DOI
https://doi.org/10.7759/cureus.94670
Primary Topic
Glioma Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Adult Medulloblastoma Presenting With Audiovestibular Symptoms and an Alternating Unterberger Test

Jeremy Rees, Christopher P Bunting, Trung Nguyen, Maria Thom et al.
Cureus
Glioma Diagnosis and Treatment
article

Adult Medulloblastoma Presenting With Audiovestibular Symptoms and an Alternating Unterberger Test

Jeremy Rees, Christopher P Bunting, Trung Nguyen, Maria Thom, Elliot Benjamin
article en

Abstract

A man in his 30s presented with a four-week history of vertigo, unilateral tinnitus, and nausea on a background of a three-year history of asymmetric audiovestibular symptoms attributed to peripheral vestibular pathology. The neurological examination was normal. A brain magnetic resonance imaging (MRI) demonstrated a fourth ventricular enhancing tumour, which was resected. The final histology was classical medulloblastoma CNS WHO Grade 4. He received craniospinal irradiation and adjuvant chemotherapy. Two years after treatment, he relapsed with spinal drop metastases and received palliative treatment. This case highlights that adults with medulloblastoma may present atypically with a longer history of unusual audiovestibular symptoms rather than signs of raised intracranial pressure or brainstem/cerebellar dysfunction.

CureusVol. 17(10)
Great Ormond Street Hospital (GB), Charing Cross Hospital (GB), Cleveland Clinic London (GB), National Hospital for Neurology and Neurosurgery (GB), University College London (GB)
Openalex Percentile: Top 59%
Glioma Diagnosis and Treatment
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Adult Medulloblastoma Presenting With Audiovestibular Symptoms and an Alternating Unterberger Test — Jeremy Rees, Christopher P Bunting, et al. · Cureus (2025) | TGRS Research Map | TGRS