A predictive nomogram for treatment response in osteonecrosis patients receiving denosumab with UKA: integrating bone turnover markers and functional parameters
Clinically, the 7-point improvement in HSS scores observed in Group B corresponds to a transition from 'poor' to 'good' knee function, while the 0.8-unit increase in femoral neck T-score translates into a 30% reduction in major-fracture risk over 10 years (FRAX-adjusted), indicating meaningful gains in patient mobility, pain relief, and long-term skeletal protection.
Authors
- Ling Liu (ORCID: https://orcid.org/0000-0001-6413-708X)
- Guoping Zou
- Ke Pu (ORCID: https://orcid.org/0000-0001-8655-8993)
- Yuanyuan Zeng (ORCID: https://orcid.org/0000-0002-2260-4468)
- RijiangChen
Institutions
- Fujian Medical University (CN)
- First Affiliated Hospital of Fujian Medical University (CN)
Publication Details
- Journal
- Endocrine Connections
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1530/ec-25-0428
- Primary Topic
- Bone and Joint Diseases
- Type
- article
- Field-Weighted Citation Impact
- 0.00