Comparative Bioavailability of Methylphenidate Powder for Prolonged-Release Oral Suspension and Methylphenidate Prolonged-Release Chewable Tablets versus Methylphenidate Immediate-Release Tablets: Phase 1, Single-Dose, Randomised, Crossover Studies i
The methylphenidate PR oral suspension and chewable tablet formulations are bioequivalent in terms of the total extent of exposure (AUC<sub>last</sub>) to methylphenidate IR tablets and are tolerable in healthy adults.
Authors
- Josep Antoni Ramos‐Quiroga (ORCID: https://orcid.org/0000-0003-1622-0350)
- Mohammed Bouhajib
- Marta Forcadell Ferré
- Alex Schneider-Pérez
Institutions
- Universitat Autònoma de Barcelona (ES)
- Centro de Investigación Biomédica en Red de Salud Mental (ES)
- Vall d'Hebron Institut de Recerca (ES)
- Neuraxpharm (Spain) (ES)
- Centre for Biomedical Network Research on Rare Diseases (ES)
- Vall d'Hebron Hospital Universitari (ES)
- Pharma Medica Research (Canada) (CA)
Publication Details
- Journal
- Clinical Drug Investigation
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1007/s40261-025-01474-3
- Primary Topic
- Attention Deficit Hyperactivity Disorder
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Neuraxpharm