The Clinical Significance of <scp>CD371</scp> Expression Detected by Flow Cytometry in Primary Myelofibrosis
This study provides the first characterization of CD371 expression patterns in PMF, showing significantly different expression profiles compared to controls. While CD371 demonstrated comparable performance to standard markers (CD34/CD38/CD13/CD33) and showed better discrimination than CD123/HLA-DR, these preliminary findings suggest its potential utility for: (1) identifying abnormal CD34<sup>+</sup>CD117<sup>+</sup> populations in PMF, and (2) possible integration into routine clinical workflows, pending further validation in larger cohorts.
Authors
- Qian Yang (ORCID: https://orcid.org/0000-0002-8797-1824)
- Qin Youwen (ORCID: https://orcid.org/0000-0003-4659-8442)
- Zhang Bingyao (ORCID: https://orcid.org/0009-0001-8898-1936)
- Fu Zhaoqiang
- Zhang Xuxi (ORCID: https://orcid.org/0009-0005-0368-7279)
Institutions
- Shanghai Traditional Chinese Medicine Hospital (CN)
Publication Details
- Journal
- International Journal of Laboratory Hematology
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1111/ijlh.70015
- Primary Topic
- Myeloproliferative Neoplasms: Diagnosis and Treatment
- Type
- article
- Field-Weighted Citation Impact
- 0.00