Central eye movement abnormalities in patients with SMA types II and III
In this study, we performed a comprehensive evaluation of eye movement function with VNG in patients with SMA. Our findings indicate that while extraocular muscles remain unaffected in SMA, subtle central oculomotor control abnormalities-likely involving supranuclear and/or cerebellar pathways-may accompany the disease and can be quantitatively detected using VNG.
Authors
- Eyyüp Kara (ORCID: https://orcid.org/0000-0002-4015-4560)
- Melih Tütüncü (ORCID: https://orcid.org/0000-0002-9851-7002)
- Nurten Uzun Adatepe (ORCID: https://orcid.org/0000-0002-1429-2249)
- Ahmet Ataş (ORCID: https://orcid.org/0000-0002-8673-6793)
- Ahmet Özdoğan
- Feray Karaali Savrun (ORCID: https://orcid.org/0000-0003-4603-2852)
- Melda Acar (ORCID: https://orcid.org/0000-0002-0906-5244)
- Bade Güleç (ORCID: https://orcid.org/0000-0002-2340-4409)
- Yeşim Oruç (ORCID: https://orcid.org/0000-0001-7888-8108)
- Ayşegül Gündüz (ORCID: https://orcid.org/0000-0003-2365-0850)
- Ceren Aliş (ORCID: https://orcid.org/0000-0001-9433-4826)
- Rişvan Deniz
Institutions
- Sakarya University (TR)
- Koç University (TR)
- Istanbul University-Cerrahpaşa (TR)
Publication Details
- Journal
- Neurophysiologie Clinique
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1016/j.neucli.2025.103112
- Primary Topic
- Neurogenetic and Muscular Disorders Research
- Type
- article
- Field-Weighted Citation Impact
- 0.00