Comparative Responsiveness of Preference-Based Health-Related Quality of Life, Social Care, and Well-Being Measures in the Context of Multiple Sclerosis

The ICECAP-A, ASCOT, and MSIS-8D were more responsive than the EQ-5D-3L in the context of MS when compared using standardized scores. The increased responsiveness of EQ-5D-3L when absolute values were used seems an artefact of the wide-ranging scale of this measure. This illustrates how the maximum potential range of values for a given PBM tariff could influence whether an intervention is found to be cost-effective.

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Publication Details

Journal
Value in Health
Published
2025-10-15
DOI
https://doi.org/10.1016/j.jval.2025.09.3063
Primary Topic
Health Systems, Economic Evaluations, Quality of Life
Type
article
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article

Comparative Responsiveness of Preference-Based Health-Related Quality of Life, Social Care, and Well-Being Measures in the Context of Multiple Sclerosis

Rod Middleton, Jeremy Chataway, Nia Morrish, Annie Hawton et al.
Value in Health
Health Systems, Economic Evaluations, Quality of Life
article

Comparative Responsiveness of Preference-Based Health-Related Quality of Life, Social Care, and Well-Being Measures in the Context of Multiple Sclerosis

Rod Middleton, Jeremy Chataway, Nia Morrish, Annie Hawton, Sarah Thomas, Kate Boddy, Amy Heather, Jennifer A. Freeman, Elizabeth Goodwin
article en

Abstract

The ICECAP-A, ASCOT, and MSIS-8D were more responsive than the EQ-5D-3L in the context of MS when compared using standardized scores. The increased responsiveness of EQ-5D-3L when absolute values were used seems an artefact of the wide-ranging scale of this measure. This illustrates how the maximum potential range of values for a given PBM tariff could influence whether an intervention is found to be cost-effective.

Value in HealthVol. 29(3)
Queen Mary University of London (GB), University of Exeter (GB), Swansea University (GB), National Hospital for Neurology and Neurosurgery (GB), University College London (GB), Peninsula College of Medicine and Dentistry (GB), University of Plymouth (GB), Bournemouth University (GB)
Openalex Percentile: Top 62%
Health Systems, Economic Evaluations, Quality of Life
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Comparative Responsiveness of Preference-Based Health-Related Quality of Life, Social Care, and Well-Being Measures in the Context of Multiple Sclerosis — Rod Middleton, Jeremy Chataway, et al. · Value in Health (2025) | TGRS Research Map | TGRS