Validation and clinical application of the hereditary hemorrhagic telangiectasia-specific quality of life scale
This study successfully externally validates the HHT-QoL. The HHT-QoL is a validated disease-specific HRQoL instrument with defined severity classification and minimal clinically important difference, making it ideal for use in clinical trials of bleeding in HHT.
Authors
- Miles Conrad (ORCID: https://orcid.org/0000-0002-7583-0493)
- Marianne S. Clancy (ORCID: https://orcid.org/0000-0001-9394-9271)
- Kevin J. Whitehead (ORCID: https://orcid.org/0000-0003-0419-7309)
- Sonia M. Thomas (ORCID: https://orcid.org/0000-0002-4930-2275)
- Keith R. McCrae (ORCID: https://orcid.org/0000-0001-7340-475X)
- Clifford R. Weiss (ORCID: https://orcid.org/0000-0003-2180-1731)
- Raj S. Kasthuri (ORCID: https://orcid.org/0000-0001-6672-3082)
- Allyson M. Pishko (ORCID: https://orcid.org/0000-0001-9997-454X)
- Joseph G. Parambil (ORCID: https://orcid.org/0000-0002-5742-4774)
- Hanny T. Al-Samkari (ORCID: https://orcid.org/0000-0001-6175-1383)
- Benjamin Carper (ORCID: https://orcid.org/0000-0001-5882-2232)
- Jake E. Decker
- Vivek Iyer (ORCID: https://orcid.org/0000-0001-6441-9319)
- Marc Zumberg (ORCID: https://orcid.org/0000-0002-9552-475X)
- Jenny Y. Zhou (ORCID: https://orcid.org/0000-0002-7446-4946)
Institutions
- University of North Carolina at Chapel Hill (US)
- Cleveland Clinic (US)
- Mayo Clinic (US)
- Johns Hopkins University (US)
- University of San Diego (US)
- RTI International (US)
- University of California, San Francisco (US)
- Medical College of Wisconsin (US)
- University of Utah (US)
- University of Florida (US)
- University of California San Diego (US)
- Massachusetts General Hospital (US)
- Mayo Clinic in Arizona (US)
- Mayo Clinic in Florida (US)
- Monkton Hall Hospital (GB)
- University of Pennsylvania (US)
Publication Details
- Journal
- Journal of Thrombosis and Haemostasis
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1016/j.jtha.2025.09.024
- Citations
- 1
- Primary Topic
- Vascular Anomalies and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 1.63