Birth Month Matters in Timing of Seasonal Prevention of Severe Respiratory Syncytial Virus

Birth month significantly influences the risk of severe RSV infections in children under 2 years of age in countries with a temperate climate and four annual seasons such as Denmark. Birth months of September through February are associated with significantly higher risks of being hospitalised with RSV infection. These insights should inform national RSV preventive strategies, including maternal vaccination and neonatal immunisation with monoclonal antibodies in countries with similar climates to optimise timing and efficacy.