Comparison of vaginal stenosis following vault brachytherapy monotherapy between common fractionation schemes in the treatment of endometrial cancer
Our findings suggest that treatment with 21Gy/3fx prescribed to 5 mm depth increased the risk of developing vaginal stenosis compared to 30Gy/5fx prescribed to surface. Patient age, BMI, cancer histology, receipt of systemic therapy, sexual activity, dilator use, treatment length, and dilator size did not appear to affect the odds of stenosis. Further prospective data would be beneficial.
Authors
- Ronald D. Alvarez (ORCID: https://orcid.org/0000-0002-0933-5398)
- Lauren S. Prescott (ORCID: https://orcid.org/0000-0002-1006-8645)
- Alyssa Brown (ORCID: https://orcid.org/0000-0002-1064-8818)
- Marta A. Crispens (ORCID: https://orcid.org/0000-0002-2334-0011)
- Courtney A. Penn (ORCID: https://orcid.org/0000-0001-7671-5895)
- H. Steve Byrd
- Marc L. Kessler
- Godwin Emeka-Ibe
- Ashwin Shinde (ORCID: https://orcid.org/0000-0002-9275-4074)
- Guillermo Oropeza Sosa
Institutions
- Vanderbilt University Medical Center (US)
Publication Details
- Journal
- Brachytherapy
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1016/j.brachy.2025.09.004
- Primary Topic
- Endometrial and Cervical Cancer Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00