Effects of Intensive Blood Pressure Control in Patients With Frailty
Hypertensive patients with high cardiovascular risk benefit from the treatment strategy of targeting systolic BP <120 mm Hg, regardless of their frailty status. In addition, the effects of intensive treatment on experiencing adverse events did not differ by frailty status. (The Effects of intensive Systolic blood Pressure lowering treatment in reducing RIsk of vascular evenTs [ESPRIT]; NCT04030234).
Authors
- Jieyun Liu
- Jiangling Liu (ORCID: https://orcid.org/0000-0002-7260-1329)
- Lei Dong
- Na Zhai (ORCID: https://orcid.org/0000-0002-4261-943X)
- Jun Qian (ORCID: https://orcid.org/0000-0001-7697-2875)
- Qiang Zhang (ORCID: https://orcid.org/0009-0007-5042-3035)
- Qiaojuan Ma
- Ying Sun (ORCID: https://orcid.org/0000-0003-0347-6269)
- Shitian Li (ORCID: https://orcid.org/0009-0002-9082-4339)
- Jiahui Ruan
- Xiqing Wei (ORCID: https://orcid.org/0000-0001-5122-4774)
- Yue Peng (ORCID: https://orcid.org/0009-0002-3840-7677)
- Jingkuo Li (ORCID: https://orcid.org/0000-0002-7806-5387)
- Sheng Li (ORCID: https://orcid.org/0000-0003-1205-8632)
- Yong Liu (ORCID: https://orcid.org/0000-0001-7771-4181)
- Ping Zhang (ORCID: https://orcid.org/0000-0001-9163-6191)
- Haibo Zhang (ORCID: https://orcid.org/0000-0001-6153-5568)
- Zuo‐Feng Zhang (ORCID: https://orcid.org/0000-0002-4669-3995)
- Yan Li (ORCID: https://orcid.org/0000-0002-2781-2119)
- Weijun Huang (ORCID: https://orcid.org/0009-0003-6592-2663)
- Lingshan Zhao (ORCID: https://orcid.org/0000-0003-4336-8975)
- Jiamin Liu (ORCID: https://orcid.org/0000-0003-4078-1772)
- Chun An
- Xiaofang Yan
Institutions
- Yuncheng University (CN)
- Chinese Academy of Medical Sciences & Peking Union Medical College (CN)
- Chinese PLA General Hospital (CN)
- Zhumadian Central Hospital (CN)
- Rush Children's Hospital (US)
- Shenyang First People's Hospital (CN)
- Luoyang Central Hospital Affiliated to Zhengzhou University (CN)
- Taiyuan Central Hospital (CN)
- Community Health Center (US)
- Masteel (China) (CN)
- Tongji Hospital (CN)
- Cixian People's Hospital (CN)
- Fu Wai Hospital (CN)
- Affiliated Hospital of Jining Medical University (CN)
Publication Details
- Journal
- Journal of the American College of Cardiology
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1016/j.jacc.2025.08.092
- Citations
- 3
- Primary Topic
- Frailty in Older Adults
- Type
- article
- Field-Weighted Citation Impact
- 3.67