Rapid design and characterization of natural binary nanocomposite (nanocellulose/nano calcium fluoride) for teeth remineralization

Background: Nanocellulose derived from agricultural waste offers sustainable potential for biomedical applications. Aim: To synthesize nanocellulose-based nanocomposite with nano calcium fluoride and evaluate its adhesion to dental surfaces. Methodology: Nanocellulose was synthesized from rice husk via chemical and ultrasonic treatment. The nanocellulose/nano calcium fluoride (NC/nCaF2) nanocomposite was formed using ultrasound. Characterization was performed using Fourier Transform Infrared Spectroscopy, X-ray Diffraction, Scanning Electron Microscope and Transmission Electron Microscope. Results: Fourier Transform Infrared Spectroscopy confirmed cellulose integrity; X-ray Diffraction revealed 66.3% crystallinity. Scanning Electron Microscope and Transmission Electron Microscope showed structural features and successful nanoparticle integration. The nanocomposite adhered effectively to tooth surfaces, with thickness around 2 ± 2.5 µm. Conclusion: The NC/nCaF2 nanocomposite demonstrated promising potential for tooth remineralization and biomedical applications.