Colistin- and octenidine-induced selective pressure on Pseudomonas aeruginosa clinical isolates in vitro: Antimicrobial activity and mechanisms of cross-resistance

Rare mutations triggered within P. aeruginosa by OCT during long-term in vitro exposure showed no impact on the efficacy of OCT and did not select for other antiseptic or antibiotic cross-resistance.

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Journal
Journal of Global Antimicrobial Resistance
Published
2025-10-15
DOI
https://doi.org/10.1016/j.jgar.2025.10.008
Primary Topic
Antibiotic Resistance in Bacteria
Type
article
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0.00
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OCT
article

Colistin- and octenidine-induced selective pressure on Pseudomonas aeruginosa clinical isolates in vitro: Antimicrobial activity and mechanisms of cross-resistance

Patrice Nordmann, Otávio Hallal Ferreira Raro, Samanta Freire, Laurent Poirel
Journal of Global Antimicrobial Resistance
Antibiotic Resistance in Bacteria
article

Colistin- and octenidine-induced selective pressure on Pseudomonas aeruginosa clinical isolates in vitro: Antimicrobial activity and mechanisms of cross-resistance

Patrice Nordmann, Otávio Hallal Ferreira Raro, Samanta Freire, Laurent Poirel
article en

Abstract

Rare mutations triggered within P. aeruginosa by OCT during long-term in vitro exposure showed no impact on the efficacy of OCT and did not select for other antiseptic or antibiotic cross-resistance.

Journal of Global Antimicrobial ResistanceVol. 45
University of Fribourg (CH)
Openalex Percentile: Top 76%
Antibiotic Resistance in Bacteria
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Colistin- and octenidine-induced selective pressure on Pseudomonas aeruginosa clinical isolates in vitro: Antimicrobial activity and mechanisms of cross-resistance — Patrice Nordmann, Otávio Hallal Ferreira Raro, et al. · Journal of Global Antimicrobial Resistance (2025) | TGRS Research Map | TGRS