Optimizing early diagnosis and treatment of acanthamoeba keratitis through corneal scraping

Elevated SPK is the most frequent early feature of AK and may mimic contact lens-related sterile keratitis. Corneal scraping is a valuable diagnostic tool that enables earlier detection and improved outcomes. PHMB monotherapy is effective in early AK, while delayed diagnosis and prior steroid use may lead to disease progression and necessitate surgical intervention.

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Publication Details

Journal
Journal of Optometry
Published
2025-10-15
DOI
https://doi.org/10.1016/j.optom.2025.100566
Primary Topic
Legionella and Acanthamoeba research
Type
article
Field-Weighted Citation Impact
0.00
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article

Optimizing early diagnosis and treatment of acanthamoeba keratitis through corneal scraping

Yu‐Chih Hou, Yu-Wei Kuo, Wen-Hui Chang
Journal of Optometry
Legionella and Acanthamoeba research
article

Optimizing early diagnosis and treatment of acanthamoeba keratitis through corneal scraping

Yu‐Chih Hou, Yu-Wei Kuo, Wen-Hui Chang
article en

Abstract

Elevated SPK is the most frequent early feature of AK and may mimic contact lens-related sterile keratitis. Corneal scraping is a valuable diagnostic tool that enables earlier detection and improved outcomes. PHMB monotherapy is effective in early AK, while delayed diagnosis and prior steroid use may lead to disease progression and necessitate surgical intervention.

Journal of OptometryVol. 19(1)
Cathay General Hospital (TW), National Taiwan University Hospital (TW)
Openalex Percentile: Top 74%
Legionella and Acanthamoeba research
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