Neutropenic sepsis and septic shock in ICU patients: A single-center experience over the last decade

Intensivists are admitting patients with neutropenic sepsis who are older and have more comorbidities than was the case in earlier years. Despite this change, there is a non-statistically significant trend of declining mortality. Our findings support the initiation at ICU admission of combination antibiotic therapy including an aminoglycoside.

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Publication Details

Journal
PLoS ONE
Published
2025-10-15
DOI
https://doi.org/10.1371/journal.pone.0334511
Primary Topic
Sepsis Diagnosis and Treatment
Type
article
Field-Weighted Citation Impact
0.00
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article

Neutropenic sepsis and septic shock in ICU patients: A single-center experience over the last decade

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Neutropenic sepsis and septic shock in ICU patients: A single-center experience over the last decade

Soraya Benguerfi, Laetitia Aubert, Jean Reignier, David Boutoille, Florian Guillotin, Emmanuel Canet, Thomas Gastinne, Jean-Baptiste Lascarrou, Matilde Karakachoff, Alice Vennier, Reyes Muñoz Calahorro
article en

Abstract

Intensivists are admitting patients with neutropenic sepsis who are older and have more comorbidities than was the case in earlier years. Despite this change, there is a non-statistically significant trend of declining mortality. Our findings support the initiation at ICU admission of combination antibiotic therapy including an aminoglycoside.

PLoS ONEVol. 20(10)
Inserm (FR), Centre Hospitalier Universitaire de Nantes (FR), Centre d'Investigation Clinique de Nantes (FR), Nantes Université (FR)
Openalex Percentile: Top 61%
Sepsis Diagnosis and Treatment
DOIOpen Access PDFOpenAlex
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Neutropenic sepsis and septic shock in ICU patients: A single-center experience over the last decade — Soraya Benguerfi, Laetitia Aubert, et al. · PLoS ONE (2025) | TGRS Research Map | TGRS