Clinical specificities and outcome of LGI1-antibody encephalitis according to age, sex and HLA
Age appears to be the main driver of clinical presentation, severity and outcome in LGI1-Ab encephalitis. Remarkably, <i>DRB1*07:01</i> non-carriers are younger, more commonly female and experience poorer prognosis, reflecting a distinct pathophysiology.
Authors
- Vicente Peris Sempere
- Antonio Farina (ORCID: https://orcid.org/0000-0002-5551-0185)
- David Gonçalves (ORCID: https://orcid.org/0000-0002-7707-0918)
- Raffaele Federico Iorio (ORCID: https://orcid.org/0000-0002-6270-0956)
- Marie Bénaiteau (ORCID: https://orcid.org/0009-0005-2347-6006)
- Géraldine Picard (ORCID: https://orcid.org/0000-0003-1282-267X)
- Alberto Vogrig (ORCID: https://orcid.org/0000-0002-3652-7061)
- Lucia Campetella (ORCID: https://orcid.org/0000-0003-3415-6428)
- Dimitri Psimaras (ORCID: https://orcid.org/0000-0002-6641-288X)
- Nicolás Lundahl Ciano-Petersen (ORCID: https://orcid.org/0000-0001-9555-4847)
- Marine Villard (ORCID: https://orcid.org/0000-0002-1061-2321)
- Macarena Villagrán‐García (ORCID: https://orcid.org/0000-0001-9236-2428)
- Véronique Rogemond (ORCID: https://orcid.org/0000-0003-2098-920X)
- Jérôme Honnorat (ORCID: https://orcid.org/0000-0002-4721-5952)
- Sergio Muñiz‐Castrillo (ORCID: https://orcid.org/0000-0001-5958-3288)
- Vincent Navarro (ORCID: https://orcid.org/0000-0003-0077-8114)
- Emmanuel Mignot (ORCID: https://orcid.org/0000-0002-6928-5310)
- Bastien Joubert (ORCID: https://orcid.org/0000-0003-4631-3056)
Institutions
- Université Claude Bernard Lyon 1 (FR)
- Università Cattolica del Sacro Cuore (IT)
- University of Udine (IT)
- Centre National de la Recherche Scientifique (FR)
- Inserm (FR)
- Agostino Gemelli University Polyclinic (IT)
- Sorbonne Université (FR)
- Research Institute Hospital 12 de Octubre (ES)
- Fundación Pública Andaluza para la Investigación de Málaga en Biomedicina y Salud (ES)
- Assistance Publique – Hôpitaux de Paris (FR)
- Hospices Civils de Lyon (FR)
- Hospital Universitario 12 De Octubre (ES)
- Stanford Health Care (US)
- Hospital Regional Universitario de Málaga (ES)
- Hôpital Lyon Sud (FR)
- Pitié-Salpêtrière Hospital (FR)
- Ospedale Santa Maria della Misericordia di Udine (IT)
- Institut de Psychiatrie et Neurosciences de Paris (FR)
- Stanford Medicine (US)
- Andalusian Centre for Nanomedicine and Biotechnology (ES)
- Hôpital Charles-Foix (FR)
- Epilepsy Foundation (AU)
- Stanford University (US)
Publication Details
- Journal
- Journal of Neurology Neurosurgery & Psychiatry
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1136/jnnp-2025-335960
- Primary Topic
- Autoimmune Neurological Disorders and Treatments
- Type
- article
- Field-Weighted Citation Impact
- 0.00