Precise staging of severe fever with thrombocytopenia syndrome: Integrating the extent of organ damage for prognostic and therapeutic applications
The progression of SFTS can be distinctly categorized into five distinct stages. Day 7 represents a critical juncture in disease progression, whereas Day 11 signifies a pivotal moment for clinical recovery. The progression stage is optimal for intervening to prevent further disease advancement. Treatment strategies should be adapted to the evolving patterns and severity of organ dysfunction. Myocarditis remains a significant challenge throughout SFTS progression, and early IVIG administration has been demonstrated to reduce mortality in patients with myocarditis complications significantly.
Authors
- Jing Sun (ORCID: https://orcid.org/0000-0002-4646-1174)
- Yingchun Sun (ORCID: https://orcid.org/0000-0003-0120-5545)
- Qiongle Wu
- Jianghua Yang (ORCID: https://orcid.org/0000-0002-0443-2455)
- Hao Yao (ORCID: https://orcid.org/0000-0001-6444-7758)
- Aiping Zhang (ORCID: https://orcid.org/0009-0000-9969-9437)
- Xiaoyi Wang (ORCID: https://orcid.org/0009-0005-7468-9685)
- Manman Liang
- Zhiyu Pan (ORCID: https://orcid.org/0000-0002-9310-329X)
Institutions
- Wannan Medical College (CN)
- Jiangsu Province Hospital (CN)
- First Affiliated Hospital of Wannan Medical College (CN)
- Nanjing Medical University (CN)
Publication Details
- Journal
- PLoS neglected tropical diseases
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1371/journal.pntd.0013249
- Citations
- 1
- Primary Topic
- Viral Infections and Vectors
- Type
- article
- Field-Weighted Citation Impact
- 1.40