COVID-19 Vaccine Effectiveness in Patients With Hematologic Malignancies: A Nationwide Cohort Study
COVID-19 vaccination lowered the risk of severe COVID-19 in SARS-CoV-2-infected patients with hematologic malignancies, although these patients remained at elevated risk compared with others. Determinants of severe COVID-19 included type of malignancy, time interval between malignancy diagnosis and SARS-CoV-2 infection, and treatment. These data can guide healthcare professionals in designing additional prevention and therapeutic strategies against respiratory virus infections for patients with hematologic malignancies.
Authors
- Caren van Roekel (ORCID: https://orcid.org/0000-0002-1247-8103)
- Astrid A.M. van der Veldt (ORCID: https://orcid.org/0000-0003-0446-1907)
- Jarom Heijmans (ORCID: https://orcid.org/0000-0001-9615-7851)
- Quincy Hofsink (ORCID: https://orcid.org/0009-0004-0216-7071)
- Susan Hahné
- Birgit I. Lissenberg‐Witte (ORCID: https://orcid.org/0000-0001-9448-1826)
- Brechje de Gier (ORCID: https://orcid.org/0000-0002-9067-090X)
- Nicolette F. de Keizer (ORCID: https://orcid.org/0000-0002-6651-1730)
- Sabine Haggenburg (ORCID: https://orcid.org/0000-0003-4095-9307)
- Annika van Roon
- Abraham Goorhuis (ORCID: https://orcid.org/0000-0001-7423-6217)
- Mette D. Hazenberg (ORCID: https://orcid.org/0000-0002-5113-0249)
- Elisabeth G.E. de Vries (ORCID: https://orcid.org/0000-0002-8949-7425)
- Jeanet M. Kemmeren (ORCID: https://orcid.org/0000-0002-4412-7615)
- Avinash G. Dinmohamed (ORCID: https://orcid.org/0000-0002-4767-6716)
- Susan van den Hof (ORCID: https://orcid.org/0000-0002-2968-9652)
- Inger S. Nijhof
- Caroline E. Rutten
- Joyce Pijpers (ORCID: https://orcid.org/0000-0001-8738-3590)
- Peter C. Huijgens
- Paul den Tex
Institutions
- University Medical Center Groningen (NL)
- University of Groningen (NL)
- Erasmus MC (NL)
- Intensive Care Foundation (AU)
- Sanquin (NL)
- St. Antonius Ziekenhuis (NL)
- National Institute for Public Health and the Environment (NL)
- Amsterdam Neuroscience (NL)
- Netherlands Comprehensive Cancer Organisation (NL)
- Erasmus MC Cancer Institute (NL)
- Amsterdam University Medical Centers (NL)
- Cancer Center Amsterdam (NL)
- Amsterdam University of Applied Sciences (NL)
- Vrije Universiteit Amsterdam (NL)
- University of Amsterdam (NL)
- Amsterdam UMC Location Vrije Universiteit Amsterdam (NL)
- Erasmus University Rotterdam (NL)
Publication Details
- Journal
- The Journal of Infectious Diseases
- Published
- 2025-10-11
- DOI
- https://doi.org/10.1093/infdis/jiaf523
- Primary Topic
- COVID-19 and healthcare impacts
- Type
- article
- Field-Weighted Citation Impact
- 0.00