A Randomized Controlled Trial of a Partially Hydrolyzed Formula on Comfort Measures in Fussy Infants
In infants with parent-perceived fussiness, a partially hydrolyzed cow milk protein formula with an added prebiotic blend, INV-PHP, does not decrease fussiness when compared with control formula but does reduce crying and excessive crying.The study was registered at clinicaltrials.gov as NCT05245422.
Authors
- Nafees Khan
- Stephen Boyd (ORCID: https://orcid.org/0000-0001-8353-6000)
- Michelle M Bohan Brown (ORCID: https://orcid.org/0000-0002-7959-9225)
- Weihong Zhuang
- Michael Yeiser
- Sisi Cao (ORCID: https://orcid.org/0000-0002-7413-295X)
- Veronica Fabrizio
- Jennifer L. Wampler (ORCID: https://orcid.org/0000-0001-6116-711X)
- Nancy Moore
- Stuart Johnson (ORCID: https://orcid.org/0000-0001-9548-229X)
- Philip Boucher
- Steven S. Wu (ORCID: https://orcid.org/0000-0001-5071-6152)
- Christopher Davis (ORCID: https://orcid.org/0000-0002-5583-4817)
- Ashley C. Patterson
- Katosha Muse
- Fred Ogwara
Institutions
- Prisma Health (US)
- Owensboro Health (US)
- Mead Johnson (United States) (US)
- John Deere (United States) (US)
- Methodist Healthcare (US)
- Alabama Clincal Therapeutics (US)
- Iowa Academy of Science (US)
- Reconstruction of a Survivor (US)
- Frontier Agriculture (United Kingdom) (GB)
- Indiana University School of Medicine
- Indiana University (US)
Publication Details
- Journal
- Current Developments in Nutrition
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1016/j.cdnut.2025.107574
- Primary Topic
- Infant Health and Development
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- Mead Johnson Nutrition