Impact of MALDI-TOF implementation and antimicrobial stewardship programs on the optimization of antibiotic therapy in Staphylococcus aureus bloodstream infections

The implementation of MALDI-TOF, in conjunction with a multidisciplinary ASP, enhances early adjustment of empirical antibiotic therapy and may be associated with reduced early mortality in S. aureus bacteremia. Incorporating rapid diagnostics, especially for MRSA detection, is a key strategy to improve clinical outcomes.

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Publication Details

Journal
Enfermedades infecciosas y microbiologia clinica (English ed )
Published
2025-10-15
DOI
https://doi.org/10.1016/j.eimce.2025.06.017
Primary Topic
Bacterial Identification and Susceptibility Testing
Type
article
Field-Weighted Citation Impact
0.00
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article

Impact of MALDI-TOF implementation and antimicrobial stewardship programs on the optimization of antibiotic therapy in Staphylococcus aureus bloodstream infections

Carlos Bea Serrano, Ignacio Torres-García, Sara Vela, Javier Colomina et al.
Enfermedades infecciosas y microbiologia clinica (English ed )
Bacterial Identification and Susceptibility Testing
article

Impact of MALDI-TOF implementation and antimicrobial stewardship programs on the optimization of antibiotic therapy in Staphylococcus aureus bloodstream infections

Carlos Bea Serrano, Ignacio Torres-García, Sara Vela, Javier Colomina, Ana Isabel de Gracia-León, Andreu Belmonte-Domingo, Ana Ferrer-Ribera, Carolina Pinto-Pla, María Rosa Oltra-Sempere, Andrea de Castro-Oliver
article en

Abstract

The implementation of MALDI-TOF, in conjunction with a multidisciplinary ASP, enhances early adjustment of empirical antibiotic therapy and may be associated with reduced early mortality in S. aureus bacteremia. Incorporating rapid diagnostics, especially for MRSA detection, is a key strategy to improve clinical outcomes.

Enfermedades infecciosas y microbiologia clinica (English ed )Vol. 43(10)
Hospital Clínico Universitario de Valencia (ES), INCLIVA Health Research Institute (ES)
Openalex Percentile: Top 67%
Bacterial Identification and Susceptibility Testing
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