Abordagem de DREZotomia no manejo da dor neuropática

Introduction: DREZotomy is a type of neurosurgical treatment for pain that involves lesions in the dorsal zone of the spine, interrupting the transmission of nociceptive neural stimuli. The main indications are related to oncologic pains resistant to morphine and some cases of neuropathic pain that meet surgical criteria. Objective: To conduct a literature review to identify the effectiveness of DREZ surgery for patients with neuropathic pain and to report the consequences of this type of treatment. Method: As a search strategy, English descriptors registered in the Medical Subject Headings (MeSH) were used. For scientific support, searches were conducted on the PubMed, Medline (BVS), and Science Direct databases using the Boolean operator "OR" to associate the descriptors in the search. Result: The lesion of the dorsal root entry zone (DREZ) is still used as a treatment option for some painful conditions, as well as for spasticity in selected patients. The most commonly techniques for performing DREZotomy are microsurgical and radiofrequency coagulation DREZ. Technical difficulties in using punctures to perform radiofrequency lesions include complications such as injuries to the dorsal columns or the corticospinal tract. Conclusion: DREZotomy is an effective therapeutic option for relieving neuropathic pain in various clinical contexts. However, it is important to note that pain relief can vary among different types of conditions, with generally higher success rates in patients with nerve root avulsion and brachial plexus injuries.

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Publication Details

Journal
BioSCIENCE
Published
2025-10-15
DOI
https://doi.org/10.55684/2025.83.s1.e00015
Primary Topic
Transcranial Magnetic Stimulation Studies
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article
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article

Abordagem de DREZotomia no manejo da dor neuropática

Maria Nesryn Tiba, Alexandre Pedrosa Oliveira Moreira, Rafaela Fernandes Gonçalves, Rafael Badalotti et al.
BioSCIENCE
Transcranial Magnetic Stimulation Studies
article

Abordagem de DREZotomia no manejo da dor neuropática

Maria Nesryn Tiba, Alexandre Pedrosa Oliveira Moreira, Rafaela Fernandes Gonçalves, Rafael Badalotti, Natan De Araujo, Suzana Patricia Santos Rodrigues, Milton Manrique Rastelli-Junior
article en

Abstract

Introduction: DREZotomy is a type of neurosurgical treatment for pain that involves lesions in the dorsal zone of the spine, interrupting the transmission of nociceptive neural stimuli. The main indications are related to oncologic pains resistant to morphine and some cases of neuropathic pain that meet surgical criteria. Objective: To conduct a literature review to identify the effectiveness of DREZ surgery for patients with neuropathic pain and to report the consequences of this type of treatment. Method: As a search strategy, English descriptors registered in the Medical Subject Headings (MeSH) were used. For scientific support, searches were conducted on the PubMed, Medline (BVS), and Science Direct databases using the Boolean operator "OR" to associate the descriptors in the search. Result: The lesion of the dorsal root entry zone (DREZ) is still used as a treatment option for some painful conditions, as well as for spasticity in selected patients. The most commonly techniques for performing DREZotomy are microsurgical and radiofrequency coagulation DREZ. Technical difficulties in using punctures to perform radiofrequency lesions include complications such as injuries to the dorsal columns or the corticospinal tract. Conclusion: DREZotomy is an effective therapeutic option for relieving neuropathic pain in various clinical contexts. However, it is important to note that pain relief can vary among different types of conditions, with generally higher success rates in patients with nerve root avulsion and brachial plexus injuries.

BioSCIENCEVol. 83(S1)
Universidade Estadual do Ceará (BR), Pontifícia Universidade Católica do Paraná (BR), Centro Brasileiro de Estudos em Dermatologia (BR), Universidade Federal do Maranhão (BR)
Openalex Percentile: Top 63%
Transcranial Magnetic Stimulation Studies
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