Intraoperative hypotension and postoperative delirium among older high-risk patients undergoing major noncardiac surgery: a retrospective single-centre cohort study
Although intraoperative hypotension initially appeared to be associated with postoperative delirium, this association was no longer significant when accounting for temporal improvements in perioperative care. Intraoperative hypotension may represent a marker of historical practice patterns rather than an independent causal driver of delirium.
Authors
- Yann Gricourt (ORCID: https://orcid.org/0009-0000-3889-5696)
- Amélie Delaporte
- Daniel J. Cole (ORCID: https://orcid.org/0000-0003-2656-0877)
- Cecilia Canales (ORCID: https://orcid.org/0000-0002-8839-5689)
- Alexandre Joosten (ORCID: https://orcid.org/0000-0002-5214-4589)
- Joseph Boktor (ORCID: https://orcid.org/0000-0002-4882-3650)
- Daniel Pearce
- Theodora Wingert (ORCID: https://orcid.org/0000-0001-7149-9150)
- Maziar M. Nourian (ORCID: https://orcid.org/0000-0002-3335-9357)
- Brenton Alexander (ORCID: https://orcid.org/0000-0003-3657-0673)
- Maxime Cannesson (ORCID: https://orcid.org/0000-0003-2120-1672)
- Tristan Grogan (ORCID: https://orcid.org/0000-0001-9471-2938)
- Nancy M. Boulos (ORCID: https://orcid.org/0009-0003-1618-0296)
- Ravi Pal
- Robert A. Whittington (ORCID: https://orcid.org/0000-0001-7877-1209)
- Jason H. Tang
- Inaame Ettoumi
Institutions
- University of California, Los Angeles (US)
- Université Paris-Saclay (FR)
- University of California System (US)
- University of California San Diego (US)
- Bicêtre Hospital (FR)
Publication Details
- Journal
- BJA Open
- Published
- 2025-10-15
- DOI
- https://doi.org/10.1016/j.bjao.2025.100500
- Primary Topic
- Intensive Care Unit Cognitive Disorders
- Type
- article
- Field-Weighted Citation Impact
- 0.00
Funders
- National Institutes of Health