Developing organ dysfunction diagnostic criteria for children with cancer and post-hematopoietic cell transplantation: protocol of systematic review

By systematically reviewing and analyzing organ-specific factors associated with patient outcomes and synthesizing these findings through a modified Delphi consensus process, we aim to create consensus criteria that will be clinically relevant for pediatric oncology patients and HCT patients. These criteria will provide a foundation to guide clinical care and to support future research in this vulnerable patient population.

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Publication Details

Journal
Frontiers in Oncology
Published
2025-10-15
DOI
https://doi.org/10.3389/fonc.2025.1591263
Primary Topic
CAR-T cell therapy research
Type
article
Field-Weighted Citation Impact
0.00
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article

Developing organ dysfunction diagnostic criteria for children with cancer and post-hematopoietic cell transplantation: protocol of systematic review

Jordan Wrigley, Aimee C. Talleur, Melissa Hines, Asya Agulnik et al.
Frontiers in Oncology
CAR-T cell therapy research
article

Developing organ dysfunction diagnostic criteria for children with cancer and post-hematopoietic cell transplantation: protocol of systematic review

Jordan Wrigley, Aimee C. Talleur, Melissa Hines, Asya Agulnik, Roelie M. Wösten‐van Asperen, Anita V. Arias, Courtney Marie Rowan, Melissa M. Hudson, Md Saiful Islam, Joshua Wolf, Benjamin K Oelkers, Michael Bashir, Kimberly K. Kertis
article en

Abstract

By systematically reviewing and analyzing organ-specific factors associated with patient outcomes and synthesizing these findings through a modified Delphi consensus process, we aim to create consensus criteria that will be clinically relevant for pediatric oncology patients and HCT patients. These criteria will provide a foundation to guide clinical care and to support future research in this vulnerable patient population.

Frontiers in OncologyVol. 15
St. Jude Children's Research Hospital (US), University of Tennessee Health Science Center (US), Washington University in St. Louis (US), Riley Hospital for Children (US), Wilhelmina Children's Hospital (NL), Indiana University School of Medicine, Indiana University – Purdue University Indianapolis (US)
Openalex Percentile: Top 60%
CAR-T cell therapy research
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