Mathematical analysis of an inverse problem for a reaction-diffusion system originated in epidemiology

In this article we focus our interest on the study of an inverse problem arising in the mathematical modeling of disease transmission. The mathematical model is given by an initial boundary value problem for a reaction diffusion system. Meanwhile, the inverse problem consists in the determination of the disease and recovery transmission rates from observed measurement of the direct problem solution at some fixed time. The unknowns of the inverse problem are coefficients of the reaction term. We formulate the inverse problem as an optimization problem for an appropriate cost functional. Then, the existence of solutions of the inverse problem is deduced by proving the existence of a minimizer for the cost functional. We establish the uniqueness of identification problem. The uniqueness is a consequence of the first order necessary optimality condition and a stability of the inverse problem unknowns with respect to the observations. Moreover, we develop a numerical approximation and simulations of the inverse problem.

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Publication Details

Journal
Cubo
Published
2025-08-08
DOI
https://doi.org/10.56754/0719-0646.2702.363
Primary Topic
Mathematical and Theoretical Epidemiology and Ecology Models
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article
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article

Mathematical analysis of an inverse problem for a reaction-diffusion system originated in epidemiology

Aníbal Coronel, Esperanza Lozada, Fernando Huancas, Jorge Torres
Cubo
Mathematical and Theoretical Epidemiology and Ecology Models
article

Mathematical analysis of an inverse problem for a reaction-diffusion system originated in epidemiology

Aníbal Coronel, Esperanza Lozada, Fernando Huancas, Jorge Torres
article en

Abstract

In this article we focus our interest on the study of an inverse problem arising in the mathematical modeling of disease transmission. The mathematical model is given by an initial boundary value problem for a reaction diffusion system. Meanwhile, the inverse problem consists in the determination of the disease and recovery transmission rates from observed measurement of the direct problem solution at some fixed time. The unknowns of the inverse problem are coefficients of the reaction term. We formulate the inverse problem as an optimization problem for an appropriate cost functional. Then, the existence of solutions of the inverse problem is deduced by proving the existence of a minimizer for the cost functional. We establish the uniqueness of identification problem. The uniqueness is a consequence of the first order necessary optimality condition and a stability of the inverse problem unknowns with respect to the observations. Moreover, we develop a numerical approximation and simulations of the inverse problem.

CuboVol. 27(2)
University of Bío-Bío (CL), Metropolitan University of Technology (CL)
Openalex Percentile: Top 61%
Mathematical and Theoretical Epidemiology and Ecology Models
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