Case report: Adolescent breast hypertrophy with a tendency toward phyllodes tumor formation: first reported case in China
Adolescent breast hypertrophy is a rare and persistent condition that affects peripubertal females both physiologically and psychologically. We present a case of a 14-year-old patient with bilateral giant breast enlargement who underwent a successful reduction mammoplasty of 16.5% Body Weight. The right breast exhibited focal interstitial proliferation myofibroblasts, suggesting a potential risk for phyllodes tumor development. This finding represents a novel histopathological association, unreported in the literature and first documented in China.
Authors
- Yange Zhang (ORCID: https://orcid.org/0000-0001-5779-6263)
- Ruiheng Liao (ORCID: https://orcid.org/0000-0002-1056-5676)
- Yang Xiao (ORCID: https://orcid.org/0000-0001-8549-6794)
- Yu‐Ting Chang (ORCID: https://orcid.org/0000-0002-5912-3406)
- Zhang Zhang (ORCID: https://orcid.org/0000-0001-6603-5060)
Institutions
- Sichuan University (CN)
- West China Hospital of Sichuan University (CN)
Publication Details
- Journal
- Frontiers in Oncology
- Published
- 2025-10-15
- DOI
- https://doi.org/10.3389/fonc.2025.1652446
- Primary Topic
- Breast Lesions and Carcinomas
- Type
- article
- Field-Weighted Citation Impact
- 0.00