Dynamic frailty trajectories identify thymoma patients at high risk of postoperative muscle weakness

Preoperative frailty and its dynamic changes independently are associated with postoperative muscle weakness in thymoma patients. The Rockwood FI provides prognostic value for risk stratification, highlighting the pre-frail state as a modifiable target for prehabilitation. Integrating longitudinal frailty assessments into perioperative care may optimize recovery and survival, urging future trials to validate disease-specific thresholds and interventions.

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Publication Details

Journal
International Journal of Surgery
Published
2025-10-15
DOI
https://doi.org/10.1097/js9.0000000000003606
Primary Topic
Myasthenia Gravis and Thymoma
Type
article
Field-Weighted Citation Impact
0.00
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article

Dynamic frailty trajectories identify thymoma patients at high risk of postoperative muscle weakness

Liancai Yan, Fugui Yang, Lei Zhu, Yuming Wang et al.
International Journal of Surgery
Myasthenia Gravis and Thymoma
article

Dynamic frailty trajectories identify thymoma patients at high risk of postoperative muscle weakness

Liancai Yan, Fugui Yang, Lei Zhu, Yuming Wang, Bo Tao, Ziming Wang
article en

Abstract

Preoperative frailty and its dynamic changes independently are associated with postoperative muscle weakness in thymoma patients. The Rockwood FI provides prognostic value for risk stratification, highlighting the pre-frail state as a modifiable target for prehabilitation. Integrating longitudinal frailty assessments into perioperative care may optimize recovery and survival, urging future trials to validate disease-specific thresholds and interventions.

International Journal of SurgeryVol. 112(2)
Tongji University (CN), Shanghai Jiao Tong University (CN), Shanghai Chest Hospital (CN), Shanghai Pulmonary Hospital (CN), Shanghai East Hospital (CN)
Openalex Percentile: Top 58%
Myasthenia Gravis and Thymoma
DOIOpen Access PDFOpenAlex
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Dynamic frailty trajectories identify thymoma patients at high risk of postoperative muscle weakness — Liancai Yan, Fugui Yang, et al. · International Journal of Surgery (2025) | TGRS Research Map | TGRS