Multi-omics insights into the role of mitophagy receptor-related genes in glioma prognosis and immune microenvironment remodeling
We present and validate a 17-MRRG prognostic model that links mitophagy receptors to glioma immunosuppression and clinical outcome, and identify IFNAR2 as a functional driver. These findings provide a rationale for incorporating MRRG profiling into prognostic assessment and therapeutic decision-making in glioma.
Authors
- Zhaotao Wang (ORCID: https://orcid.org/0000-0001-5049-8626)
- Zhiqiang Peng (ORCID: https://orcid.org/0000-0001-8130-162X)
- Chunmei Chen (ORCID: https://orcid.org/0000-0002-2949-7343)
- Yuheng Xu
- Jintao Hu
- Wanqi Weng
- Yuanyi Xiong
Institutions
- Fujian University of Traditional Chinese Medicine (CN)
- Second Affiliated Hospital of Guangzhou Medical University (CN)
- Fuzhou Second Hospital (CN)
- Panyu District Central Hospital (CN)
- Guangzhou Medical University (CN)
Publication Details
- Journal
- Frontiers in Immunology
- Published
- 2025-10-15
- DOI
- https://doi.org/10.3389/fimmu.2025.1672678
- Citations
- 1
- Primary Topic
- Epigenetics and DNA Methylation
- Type
- article
- Field-Weighted Citation Impact
- 0.81