Non-resolving, Progressive, Non-ketotic Hyperglycemic Hemichorea-Hemiballismus Syndrome in an Elderly Male

Non-ketotic hyperglycemic hemichorea-hemiballismus syndrome is a rare neurological condition associated with hyperglycemia from uncontrolled diabetes mellitus. We present a case of a male patient in his late 80s with a background of T2DM who presented with a new onset of progressive involuntary movements involving the left side of his body. Imaging revealed hyperdensity in the right basal ganglia, suggestive of non-ketotic hyperglycemic hemichorea. Management included glycemic control and neuroleptic treatment, with resolution of symptoms in most cases. This case highlights the importance of considering metabolic causes of hemichorea-hemiballismus in elderly patients, glycemic control, and the correlation of these factors with quality of life.

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Publication Details

Journal
Cureus
Published
2025-10-14
DOI
https://doi.org/10.7759/cureus.94603
Primary Topic
Neurological and metabolic disorders
Type
article
Field-Weighted Citation Impact
0.00
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article

Non-resolving, Progressive, Non-ketotic Hyperglycemic Hemichorea-Hemiballismus Syndrome in an Elderly Male

Sumathi Krishnan, Cedric Cunanan, A Chandani, Omar Rage
Cureus
Neurological and metabolic disorders
article

Non-resolving, Progressive, Non-ketotic Hyperglycemic Hemichorea-Hemiballismus Syndrome in an Elderly Male

Sumathi Krishnan, Cedric Cunanan, A Chandani, Omar Rage
article en

Abstract

Non-ketotic hyperglycemic hemichorea-hemiballismus syndrome is a rare neurological condition associated with hyperglycemia from uncontrolled diabetes mellitus. We present a case of a male patient in his late 80s with a background of T2DM who presented with a new onset of progressive involuntary movements involving the left side of his body. Imaging revealed hyperdensity in the right basal ganglia, suggestive of non-ketotic hyperglycemic hemichorea. Management included glycemic control and neuroleptic treatment, with resolution of symptoms in most cases. This case highlights the importance of considering metabolic causes of hemichorea-hemiballismus in elderly patients, glycemic control, and the correlation of these factors with quality of life.

CureusVol. 17(10)
Middlesex Hospital (US), North Middlesex Hospital (GB)
Openalex Percentile: Top 61%
Neurological and metabolic disorders
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